The Antibiotic Resistance and Multidrug Resistance Pattern of Uropathogenic Escherichia coli at Soba University Hospital: A Descriptive Retrospective Survey

Background: The irrational use of antibiotics for the treatment urinary tract infections (UTIs) may lead to increased antimicrobial resistance among uropathogenic Escherichia coli (E. coli), as well multidrug worldwide, which will limit available options UTIs caused by these organisms. This study aimed determine pattern E. causing in out-patients and in-patients Soba University Hospital.
 Methods: Data were collected from laboratory records Department Microbiology Teaching Hospital using a predesigned checklist then analyzed statistical package social sciences. Bivariate analysis (Chi-square test) was used compare between variables.
 Results: Out 231 urine cultures, 160 (69.3%) females. results showed high ampicillin (92.4%), amoxicillin-clavulanic acid (83.3%), cephalexin (90.6%), cefuroxime (72%), ceftazidime (71%), ceftriaxone ciprofloxacin (68%), co-trimoxazole (75.3%). Collectively, around 188 (81.4%) multidrug-resistant. On other hand, sensitivities isolates 68.8%, 93.1%, 89.4%, 100% gentamicin, amikacin, carbapenems, respectively. 
 Conclusion: rate observed be commonly prescribed drugs UTIs, including ampicillin, amoxicillin/clavulanic acid, different cephalosporins, fluoroquinolones, co-trimoxazole. However, lower rates nitrofurantoin, carbapenems. Thus, can reserved empirical coli.